.caveat{background:#fff;border-left:3px solid var(--accent);border-top:1px solid var(--line);border-right:1px solid var(--line);border-bottom:1px solid var(--line);border-radius:0 10px 10px 0;padding:12px 16px;margin:18px 0;color:var(--muted);font-size:.92rem}.caveat__heading{margin:0 0 6px;font-size:.72rem;text-transform:uppercase;letter-spacing:.08em;color:var(--accent);font-weight:600}.caveat__body{margin:0}.strip{display:flex;flex-direction:column;gap:6px;min-width:160px}.strip__legend{display:flex;flex-wrap:wrap;gap:4px 18px;margin:0;padding:0;list-style:none;font-size:.78rem;color:var(--muted)}.strip__legend-item{display:inline-flex;align-items:baseline;gap:7px}.strip__swatch{width:10px;height:10px;border-radius:2px;transform:translateY(1px)}.strip__swatch--primary{background:var(--series-primary)}.strip__swatch--secondary{background:repeating-linear-gradient(45deg,var(--series-secondary) 0 3px,var(--series-track) 3px 6px)}.strip__legend-value{color:var(--ink);font-variant-numeric:tabular-nums}.strip__track{display:flex;gap:var(--series-gap);height:12px;background:var(--series-track);border-radius:3px;overflow:hidden}.strip__segment{display:block;height:100%}.strip__segment--primary{background:var(--series-primary)}.strip__segment--secondary{background:repeating-linear-gradient(45deg,var(--series-secondary) 0 3px,var(--series-track) 3px 6px)}.strip__caption{margin:0;font-size:.76rem;color:var(--muted)}.combo-legend{margin:0 0 12px}.combo-legend__keys{display:flex;flex-wrap:wrap;gap:14px;list-style:none;margin:0 0 4px;padding:0;font-size:.78rem;color:var(--muted)}.combo-legend__key{display:inline-flex;align-items:center;gap:6px}.combo-legend__note{margin:0;font-size:.8rem;color:var(--muted)}.exclusion{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:14px 18px;margin:18px 0}.exclusion__heading{font-size:.78rem;text-transform:uppercase;letter-spacing:.08em;color:var(--accent);margin:0 0 10px}.exclusion__list{margin:0;padding:0 0 0 18px}.exclusion__item{margin:0 0 8px;color:var(--ink);font-size:.94rem}.exclusion__rule{margin:8px 0 0;color:var(--muted);font-size:.9rem}.istrip{display:flex;flex-direction:column;gap:5px;min-width:190px}.istrip__track{position:relative;height:14px;background:var(--series-track);border-radius:3px}.istrip__track--empty{height:10px}.istrip__mark{position:absolute;top:50%;width:9px;height:9px;border-radius:50%;transform:translate(-50%,-50%);box-sizing:border-box}.istrip__mark--mean{background:var(--series-primary);border:2px solid var(--bg);width:11px;height:11px}.istrip__mark--edge{background:var(--bg);border:2px solid var(--series-primary)}.istrip__mark--static{position:static;display:inline-block;transform:translateY(1px)}.istrip__caption,.istrip__ends,.istrip__keys{margin:0;font-size:.76rem;color:var(--muted)}.istrip__ends{display:flex;justify-content:space-between}.istrip__keys{display:flex;flex-wrap:wrap;gap:4px 16px;padding:0;list-style:none}.istrip__key{display:inline-flex;align-items:center;gap:6px}.istrip__absent{color:var(--muted);font-size:.82rem}.ki{display:inline-flex;align-items:baseline;flex-wrap:wrap;gap:8px}.ki__value{font-family:var(--mono);font-size:.92rem}.ki--bound .ki__value{color:var(--muted)}.ki--unclassified .ki__value{color:var(--muted);font-style:italic}.ki--exact .ki__value{color:var(--ink);font-weight:600}.ki__species{font-size:.76rem;color:var(--muted);text-transform:lowercase;letter-spacing:.02em}.ki__species[data-non-human=true]{color:var(--warn-ink)}.ki__marker{font-style:italic}.ki__kind{font-size:.68rem;text-transform:uppercase;letter-spacing:.08em;color:var(--muted);border:1px solid var(--line);border-radius:999px;padding:1px 7px}.ki__explain{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}.low-n{display:inline-flex;align-items:baseline;gap:6px;font-size:.78rem;color:var(--warn-ink);border:1px solid var(--line);background:#fbf1dc;border-radius:999px;padding:2px 10px}.low-n__icon{font-weight:700}.status{border:1px solid var(--line);border-radius:var(--radius);background:#fff;padding:18px;margin:18px 0}.status__heading{margin:0 0 6px;font-size:.95rem;font-weight:600}.status__detail{margin:0;color:var(--muted);font-size:.9rem}.status__retry{margin-top:12px;font:inherit;font-size:.85rem;border:1px solid var(--line);background:var(--accent-soft);color:var(--accent);border-radius:999px;padding:5px 14px;cursor:pointer}.skeleton{display:flex;flex-direction:column;gap:12px;margin:18px 0}.skeleton__row{height:74px;border:1px solid var(--line);border-radius:var(--radius);background:linear-gradient(90deg,#fff 0%,var(--accent-soft) 50%,#fff 100%)}.source-banner{background:#fff;border:1px solid var(--line);border-left:3px solid var(--warn);border-radius:0 10px 10px 0;padding:12px 16px;margin:18px 0}.source-banner__heading{margin:0 0 6px;font-weight:600;font-size:.92rem;color:var(--warn-ink);display:flex;align-items:baseline;gap:8px}.source-banner__body{margin:0 0 6px;color:var(--muted);font-size:.9rem}.source-banner__vintage{margin:0;color:var(--muted);font-size:.8rem;font-family:var(--mono)}.withheld{background:#fff;border-left:3px solid var(--warn);border-top:1px solid var(--line);border-right:1px solid var(--line);border-bottom:1px solid var(--line);border-radius:0 10px 10px 0;padding:12px 16px;margin:18px 0;color:var(--muted);font-size:.92rem}.withheld__heading{margin:0 0 6px;font-size:.72rem;text-transform:uppercase;letter-spacing:.08em;color:var(--warn-ink);font-weight:600}.withheld__icon{margin-right:8px}.withheld__body{margin:0 0 6px}.withheld__body:last-child{margin-bottom:0}.withheld__meta{margin:0 0 6px;font-size:.86rem}.agraph__counts{margin:0 0 10px;font-size:.9rem;color:var(--muted)}.agraph__warnings{margin:0;padding-left:18px;font-size:.86rem}.agraph__empty{margin:14px 0;font-size:.92rem;color:var(--muted)}.agraph__legend{border:1px solid var(--line);border-radius:var(--radius);padding:12px 14px;margin:0 0 14px}.agraph__legend-heading{margin:0 0 8px;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__legend-heading--sub{margin-top:12px}.agraph__legend-list{margin:0;padding:0;list-style:none;display:grid;gap:7px;font-size:.86rem}.agraph__legend-list li{display:grid;grid-template-columns:34px 1fr;align-items:center;gap:10px}.agraph__legend-note{margin:0;font-size:.86rem;color:var(--muted)}.agraph__swatch{display:block;height:0;border-top-style:solid}.agraph__swatch[data-kind=binding]{border-top-width:2px;border-top-color:var(--muted)}.agraph__swatch[data-kind=correlation]{border-top-width:4px;border-top-color:var(--series-primary)}.agraph__swatch[data-kind=observation]{border-top-width:2px;border-top-color:var(--series-secondary)}.agraph__swatch[data-dashed=true]{border-top-style:dashed;border-top-width:2px;border-top-color:var(--muted)}.agraph__figure{margin:0;max-width:100%;overflow:auto;border:1px solid var(--line);border-radius:var(--radius);padding:8px;background:#fff}.agraph__svg{display:block;max-width:none}.agraph__scroll-hint{margin:0 0 8px;font-size:.86rem;color:var(--muted);position:sticky;left:0;max-width:100%}.agraph__layer-heading{font-size:11px;font-weight:600;text-transform:uppercase;letter-spacing:.08em;fill:var(--muted)}.agraph__group-label{font-size:10px;font-weight:600;text-transform:uppercase;letter-spacing:.06em;fill:var(--muted)}.agraph__edge{stroke:var(--muted);stroke-opacity:.55}.agraph__edge[data-kind=correlation]{stroke:var(--series-primary);stroke-opacity:.5}.agraph__edge[data-kind=observation]{stroke:var(--series-secondary);stroke-opacity:.65}.agraph__edge[data-dashed=true]{stroke-dasharray:4 3}.agraph__edge[data-muted=true]{stroke-opacity:.28}.agraph__hit{fill:transparent;stroke:none}.agraph__chip{fill:var(--accent-soft);stroke:var(--line)}.agraph__label{font-size:11px;fill:var(--ink)}.agraph__node[data-kind=receptor] .agraph__chip{fill:#fff}.agraph__node[data-axis=true] .agraph__label{font-weight:600;text-transform:uppercase;letter-spacing:.05em;font-size:10px}.agraph__node[data-axis=true] .agraph__chip{fill:none;stroke:none}.agraph__node[data-muted=true] .agraph__label{fill:var(--muted)}.agraph__node[data-muted=true] .agraph__chip{fill:none}.agraph__controls{display:flex;align-items:flex-end;flex-wrap:wrap;gap:10px;border:1px solid var(--line);border-radius:var(--radius);padding:12px 14px;margin:0 0 6px}.agraph__controls-heading{align-self:center;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__control{display:flex;flex-direction:column;gap:4px}.agraph__control-label{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__input{font:inherit;font-size:.9rem;padding:6px 9px;border:1px solid var(--line);border-radius:8px;width:7rem}.agraph__input--path{font-family:var(--mono);width:15rem}.agraph__button{font:inherit;font-size:.88rem;padding:7px 12px;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.agraph__button:hover{background:var(--accent-soft)}.agraph__control-hint{flex-basis:100%;margin:2px 0 0;font-size:.82rem;color:var(--muted)}.agraph__rejected{margin:0 0 12px;font-size:.88rem;color:var(--warn-ink)}.agraph__scoped,.agraph__no-stats,.agraph__keyboard{margin:0 0 10px;font-size:.86rem;color:var(--muted)}.agraph__toggle{border:1px solid var(--line);border-radius:var(--radius);padding:10px 14px;margin:0 0 14px}.agraph__toggle-label{display:flex;align-items:center;gap:8px;font-size:.92rem}.agraph__toggle-state{margin:6px 0 0;font-size:.84rem;color:var(--muted)}.agraph__node{cursor:pointer}.agraph__node:focus{outline:none}.agraph__node:focus .agraph__chip,.agraph__node:focus-visible .agraph__chip{stroke:var(--accent);stroke-width:2}.agraph__node[data-selected=true] .agraph__chip{fill:var(--accent);stroke:var(--accent)}.agraph__node[data-selected=true] .agraph__label{fill:#fff}.agraph__node[data-deemphasised=true] .agraph__label{fill:var(--line)}.agraph__node[data-deemphasised=true] .agraph__chip{fill:none;stroke:var(--line)}.agraph__edge[data-deemphasised=true]{stroke-opacity:.08}.agraph__detail{margin-top:14px;border:1px solid var(--line);border-radius:var(--radius);padding:0 14px 12px;background:var(--bg);max-height:55vh;overflow:auto}.agraph__detail[data-selected=true]{position:sticky;bottom:0}.agraph__detail-bar{position:sticky;top:0;z-index:1;display:flex;align-items:center;justify-content:space-between;gap:10px;margin:0 -14px 8px;padding:12px 14px 8px;background:var(--bg);border-bottom:1px solid var(--line)}.agraph__detail-close{flex:none;min-width:44px;min-height:44px;font:inherit;font-size:1.3rem;line-height:1;padding:0;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.agraph__detail-close:hover{background:var(--accent-soft)}.agraph__detail-heading{margin:0;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__detail-prompt,.agraph__detail-neighbours{margin:0 0 8px;font-size:.88rem;color:var(--muted)}.agraph__detail-name{margin:0;font-size:1.05rem;font-weight:600}.agraph__detail-kind{margin:0 0 8px;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__detail-full{margin:0 0 6px;font-size:.9rem;color:var(--muted)}.agraph__detail-field,.agraph__detail-counts,.agraph__detail-definition{margin:0 0 4px;font-size:.9rem}.agraph__detail-label{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__detail-subheading{margin:12px 0 6px;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.agraph__detail-list{margin:0;padding:0;list-style:none}.agraph__detail-row{display:flex;align-items:center;flex-wrap:wrap;gap:10px;padding:5px 0;border-bottom:1px solid var(--line);font-size:.88rem}.agraph__detail-far{min-width:11rem;font-weight:500}.agraph__detail-ki{font-family:var(--mono);font-size:.84rem}.agraph__detail-species{font-size:.8rem;color:var(--warn-ink)}.agraph__detail-link{margin:12px 0 8px;font-size:.9rem}.agraph__swatch-marker{display:block;text-align:center;font-size:.95rem;color:var(--warn-ink)}.agraph__node[data-flagged=true] .agraph__label{fill:var(--warn-ink)}@media(max-width:640px){.agraph__input--path,.agraph__input,.agraph__control{width:100%}.agraph__legend-list li{grid-template-columns:34px minmax(0,1fr)}.agraph__detail-far{min-width:0}}.agraph__scope{margin:10px 0 0;padding:8px 12px;border:1px solid var(--line);border-radius:var(--radius);background:#fbf1dc}.agraph__scope-heading{margin:0;font-size:.84rem;font-weight:600;color:var(--warn-ink);display:flex;align-items:baseline;gap:6px}.agraph__scope-icon{font-weight:700}.agraph__scope-body{margin:4px 0 0;font-size:.84rem;color:var(--muted)}.agraph__drill{margin:10px 0 0;padding:8px 0 0;border-top:1px solid var(--line)}.agraph__drill-count{margin:0 0 6px;font-size:.84rem;color:var(--warn-ink);display:flex;align-items:baseline;gap:6px}.agraph__drill-state{margin:8px 0 0;font-size:.82rem;color:var(--muted)}.disclaimer{border-top:1px solid var(--line);padding:28px 0 56px;margin-top:40px;color:var(--muted);font-size:.86rem}.disclaimer__text{margin:0 0 8px;max-width:70ch}.disclaimer a{color:var(--muted);text-decoration:underline}.disclaimer__links{margin:0}.shell{display:flex;flex-direction:column;min-height:100vh;min-width:0}.shell__main{flex:1;padding:28px 24px 0;min-width:0}.shell__skip{position:absolute;left:-9999px}.shell__skip:focus{left:12px;top:12px;z-index:10;background:#fff;padding:8px 14px;border-radius:8px;border:1px solid var(--line)}.shell__header{background:linear-gradient(160deg,var(--hero-from) 0%,var(--hero-mid) 55%,var(--hero-to) 100%);color:#fff}.shell__header-inner{display:flex;flex-wrap:wrap;align-items:center;justify-content:space-between;gap:16px;padding:18px 24px}.shell__brand{display:flex;align-items:center;gap:10px;color:#fff;text-decoration:none}.shell__glyph{display:block}.shell__title{font-weight:700;font-size:1.1rem}.shell__section{font-size:.7rem;text-transform:uppercase;letter-spacing:.08em;background:#ffffff24;border:1px solid rgba(255,255,255,.25);border-radius:999px;padding:3px 9px}.shell__nav{display:flex;flex-wrap:wrap;align-items:center;gap:6px}.shell__link{color:#ece7fb;text-decoration:none;font-size:.92rem;padding:7px 12px;border-radius:8px}.shell__link:hover{background:#ffffff1a;text-decoration:none}.shell__link--active{background:#ffffff29;color:#fff;font-weight:600}.shell__link--pending{color:#e4ddf6;font-style:italic;cursor:default;font-size:.82rem}@media(max-width:640px){.shell__header-inner{padding:12px 16px;gap:10px}.shell__title{font-size:1rem}.shell__nav{gap:4px}.shell__link{padding:6px 10px;font-size:.88rem}.shell__link--pending{flex-basis:100%;padding:2px 0 0;font-size:.78rem;line-height:1.4}}.pmap__filter{display:flex;align-items:flex-end;flex-wrap:wrap;gap:10px;border:1px solid var(--line);border-radius:var(--radius);padding:12px 14px;margin:0 0 6px}.pmap__control{display:flex;flex-direction:column;gap:4px}.pmap__control-label{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.pmap__input{font:inherit;font-family:var(--mono);font-size:.9rem;padding:6px 9px;border:1px solid var(--line);border-radius:8px;min-width:15rem}.pmap__filter button{font:inherit;font-size:.88rem;padding:7px 12px;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.pmap__filter button:hover{background:var(--accent-soft)}.pmap__control-hint{flex-basis:100%;margin:2px 0 0;font-size:.82rem;color:var(--muted)}.pmap__rejected{margin:0 0 14px;font-size:.88rem;color:var(--warn-ink)}.pmap__topology-list{margin:0;padding-left:18px;color:var(--muted);font-size:.88rem}.pmap__topology-list li{margin-bottom:4px}.pmap__coverage{margin:16px 0 4px;font-weight:600}.pmap__scoped{margin:0 0 12px;font-size:.9rem;color:var(--muted)}.pmap__notes{margin:14px 0 18px;padding-left:18px;color:var(--muted);font-size:.88rem}.pmap__notes li{margin-bottom:5px}.pmap__empty{border:1px dashed var(--line);border-radius:var(--radius);padding:16px;color:var(--muted)}.pmap__toolbar{display:flex;gap:8px;margin:12px 0 8px}.pmap__toolbar button{font:inherit;font-size:.82rem;padding:5px 10px;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.pmap__toolbar button:disabled{color:var(--muted);cursor:default;opacity:.6}.pmap__tree{list-style:none;margin:0;padding:0 0 10px}.pmap__item{margin:0;padding:0}.pmap__item:focus-visible{outline:2px solid var(--accent);outline-offset:-2px;border-radius:6px}.pmap__item[aria-selected=true]>.pmap__row{background:var(--accent-soft)}.pmap__row{display:grid;grid-template-columns:16rem 5.5rem minmax(15rem,1fr) 15rem;align-items:center;column-gap:14px;padding:4px 8px;border-bottom:1px solid var(--line);cursor:pointer}.pmap__label{display:flex;align-items:center;gap:8px;min-width:0}.pmap__row:hover{background:var(--accent-soft)}.pmap__twisty{color:var(--muted);font-size:.8rem;-webkit-user-select:none;user-select:none}.pmap__name{font-family:var(--mono);font-size:.88rem;white-space:nowrap}.pmap__bar{display:block;height:8px;background:var(--series-track);border-radius:4px;overflow:hidden}.pmap__bar-fill{display:block;height:100%;background:var(--series-primary);border-radius:4px}.pmap__counts{display:flex;flex-wrap:wrap;gap:4px 10px;font-size:.82rem}.pmap__counts--zero{color:var(--muted)}.pmap__count-value{font-variant-numeric:tabular-nums;font-weight:600}.pmap__count-label{color:var(--muted)}.pmap__unobserved{grid-column:4;font-size:.78rem;font-style:italic;color:var(--muted)}.pmap__intensity{max-width:15rem}.pmap__intensity .istrip__caption{font-size:.72rem;line-height:1.35}.pmap__intensity .istrip__absent{font-size:.72rem}.pmap__detail{margin:22px 0 0;border:1px solid var(--line);border-radius:var(--radius);padding:0 18px 14px;background:#fff;box-shadow:0 -6px 18px #1a162612;max-height:45vh;overflow:auto}.pmap__detail[data-selected=true]{position:sticky;bottom:0}.pmap__detail-bar{position:sticky;top:0;z-index:1;display:flex;align-items:center;justify-content:space-between;gap:10px;margin:0 -18px 10px;padding:14px 18px 8px;background:#fff;border-bottom:1px solid var(--line)}.pmap__detail-close{flex:none;min-width:44px;min-height:44px;font:inherit;font-size:1.3rem;line-height:1;padding:0;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.pmap__detail-close:hover{background:var(--accent-soft)}.pmap__detail-heading{margin:0;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.pmap__detail-prompt{margin:0;color:var(--muted)}.pmap__detail-name{margin:0 0 6px;font-family:var(--mono);font-size:1.05rem}.pmap__detail-path,.pmap__detail-valence,.pmap__detail-definition,.pmap__detail-counts{margin:0 0 6px;font-size:.9rem}.pmap__detail-counts{display:flex;flex-wrap:wrap;gap:10px;align-items:baseline}.pmap__detail-label{font-size:.72rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.pmap__detail-intensity{margin:10px 0;max-width:22rem}.pmap__detail-clear{font:inherit;font-size:.82rem;padding:5px 10px;border:1px solid var(--line);border-radius:8px;background:#fff;color:var(--accent);cursor:pointer}.pmap__legend{max-width:26rem;margin-bottom:6px}@media(max-width:1000px){.pmap__row{grid-template-columns:minmax(7rem,16rem) minmax(4rem,5.5rem) minmax(5rem,1fr) minmax(7rem,15rem);column-gap:10px}.pmap__name{white-space:normal;overflow-wrap:anywhere}}@media(max-width:640px){.pmap__row{grid-template-columns:minmax(0,1fr);row-gap:6px;padding:8px}.pmap__twisty{font-size:1rem;min-width:24px}.pmap__name{white-space:normal;overflow-wrap:anywhere}.pmap__unobserved{grid-column:1}.pmap__intensity{max-width:none}.pmap__intensity .istrip__caption{font-size:.75rem}.pmap__input{min-width:0;width:100%}.pmap__control{width:100%}.pmap__legend{max-width:none}}.tscroll{max-width:100%;overflow-x:auto}.tscroll:focus-visible{outline:2px solid var(--accent);outline-offset:2px}@media(max-width:1000px){.tscroll table th:first-child,.tscroll table td:first-child{position:sticky;left:0;z-index:1;background:var(--bg);border-right:1px solid var(--line)}}.rdetail__back{margin:0 0 4px;font-size:.85rem}.rdetail__identity{display:flex;align-items:baseline;flex-wrap:wrap;gap:10px;margin:0 0 20px}.rdetail__full{color:var(--muted)}.rdetail__block{margin:0 0 26px}.rdetail__heading{font-size:1rem;margin:0 0 8px}.rdetail__censoring{margin:0 0 6px;font-size:.92rem}.rdetail__censoring+.strip{margin-top:10px;max-width:420px}.rdetail__no-stats,.rdetail__control-hint,.rdetail__summary{color:var(--muted);font-size:.85rem;margin:0 0 14px}.rdetail__controls{display:flex;flex-wrap:wrap;align-items:center;gap:10px 20px;padding:12px 16px;border:1px solid var(--line);border-radius:var(--radius);background:#fff;margin:0 0 8px}.rdetail__controls-heading{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.rdetail__control{display:inline-flex;align-items:baseline;gap:8px}.rdetail__control-label{font-size:.85rem;color:var(--ink)}.rdetail__input{font:inherit;font-size:.9rem;color:var(--ink);background:#fff;border:1px solid var(--line);border-radius:8px;padding:5px 8px;width:100px}.rdetail__input:focus-visible{outline:2px solid var(--accent);outline-offset:1px}.rdetail__clear{font:inherit;font-size:.85rem;color:var(--accent);background:none;border:0;padding:0;cursor:pointer;text-decoration:underline}.rdetail__rejected{color:var(--warn-ink);font-size:.85rem;margin:0 0 10px}.rdetail__notes{margin:0 0 14px;padding-left:18px;color:var(--muted);font-size:.85rem}.rdetail__notes li{margin-bottom:5px}.rdetail__notes+.istrip{max-width:260px;margin-bottom:16px}.rdetail__table{width:100%;border-collapse:collapse}.rdetail__table th{text-align:left;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted);font-weight:500;padding:0 14px 8px 0;border-bottom:1px solid var(--line)}.rdetail__table td{padding:12px 14px 12px 0;border-bottom:1px solid var(--line);vertical-align:top}.rdetail__rank{text-align:right;width:3ch;color:var(--muted);font-variant-numeric:tabular-nums;padding-right:14px}.rdetail__num{text-align:right;font-variant-numeric:tabular-nums}.rdetail__phenomenon{display:block;font-weight:500}.rdetail__path{display:block;color:var(--muted);font-size:.78rem;font-family:var(--mono);margin-bottom:4px}.rdetail__non-human{display:inline-flex;align-items:baseline;gap:6px;margin-top:5px;color:var(--warn-ink);font-size:.78rem}.rdetail__non-human-icon{font-size:.72rem}.rdetail__ki{font-size:.85rem}.rdetail__absent,.rdetail__empty,.rdetail__missing{color:var(--muted);font-size:.88rem}.rdetail__empty{border:1px solid var(--line);border-radius:var(--radius);padding:18px;margin:0}@media(max-width:1000px){.tscroll .rdetail__table th.rdetail__rank,.tscroll .rdetail__table td.rdetail__rank{width:3rem;min-width:3rem;border-right:0}.tscroll .rdetail__table thead th:nth-child(2),.tscroll .rdetail__table tbody td:nth-child(2){position:sticky;left:3rem;z-index:1;background:var(--bg);border-right:1px solid var(--line)}.rdetail__input{width:100%}.rdetail__controls{display:block}}.rlist__rule{border-left:3px solid var(--accent);background:var(--accent-soft);border-radius:0 var(--radius) var(--radius) 0;padding:12px 16px;margin:0 0 14px;color:var(--ink);font-size:.9rem}.rlist__note,.rlist__count{color:var(--muted);font-size:.85rem;margin:0 0 4px}.rlist__count{margin-bottom:12px}.rlist{width:100%;border-collapse:collapse}.rlist th{text-align:left;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted);font-weight:500;padding:0 12px 8px 0;border-bottom:1px solid var(--line)}.rlist td{padding:10px 12px 10px 0;border-bottom:1px solid var(--line);vertical-align:top}.rlist__binding{width:320px}.rlist__link{font-weight:500}.rlist__full{display:block;color:var(--muted);font-size:.82rem}.rlist__absent{color:var(--muted);font-size:.85rem}.rlist__cannot{display:inline-flex;align-items:baseline;gap:6px;margin-top:6px;color:var(--warn-ink);font-size:.8rem}.rlist__cannot-icon{font-size:.75rem}.rlist__empty{border:1px dashed var(--line);border-radius:var(--radius);padding:16px;color:var(--muted)}@media(max-width:640px){.rlist,.rlist thead,.rlist tbody,.rlist tr,.rlist th,.rlist td{display:block}.rlist thead tr{display:flex;flex-wrap:wrap;gap:6px;padding:0 0 10px;border-bottom:1px solid var(--line)}.rlist thead th{padding:0;border:0}.rlist tbody tr{border:1px solid var(--line);border-radius:var(--radius);padding:10px 12px;margin:0 0 10px}.rlist tbody td{display:flex;align-items:baseline;justify-content:space-between;gap:12px;padding:4px 0;border:0}.rlist tbody td:before{content:attr(data-label);flex:none;font-size:.78rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.rlist tbody td:first-child{display:block;padding:0 0 6px}.rlist tbody td:first-child:before{content:none}.rlist__num{text-align:left}}@media(max-width:640px){.rlist thead tr{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap;padding:0;border:0}.rlist__link{display:flex;align-items:center;min-height:44px;font-size:1.02rem}.rlist tbody td.rlist__binding{display:block;padding-top:8px}.rlist tbody td.rlist__binding:before{display:block;margin-bottom:4px}}.meter{display:flex;flex-direction:column;gap:6px}.meter__label{margin:0;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.meter__track{height:10px;border-radius:3px;background:var(--series-track);overflow:hidden}.meter__fill{display:block;height:100%;background:var(--series-primary);border-radius:0 4px 4px 0}.meter__value{margin:0;font-size:.84rem;color:var(--muted)}.meter__figure{color:var(--ink);font-weight:600;font-variant-numeric:tabular-nums}.tile{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:16px 18px;display:flex;flex-direction:column;gap:4px}.tile__label{margin:0;font-size:.72rem;text-transform:uppercase;letter-spacing:.08em;color:var(--muted)}.tile__value{margin:0;font-size:1.7rem;font-weight:600;line-height:1.15}.tile__context{margin:0;font-size:.82rem;color:var(--muted)}.tile__figure{margin-top:8px}.tile--hero{border-left:3px solid var(--accent)}.tile--hero .tile__value{font-size:3rem;letter-spacing:-.02em}.tile__suffix{font-size:.5em;font-weight:500;color:var(--muted)}.dash__hero{display:grid;grid-template-columns:minmax(280px,1fr) 2fr;gap:16px;margin:22px 0}.dash__tiles{display:grid;grid-template-columns:repeat(auto-fit,minmax(190px,1fr));gap:16px}.dash__block{margin:34px 0}.dash__heading{font-size:1.02rem;margin:0 0 4px;letter-spacing:-.01em}.dash__subheading{font-size:.86rem;text-transform:uppercase;letter-spacing:.07em;color:var(--muted);margin:26px 0 4px}.dash__explain{margin:12px 0 0;color:var(--muted);font-size:.9rem;max-width:78ch}.dash__note{margin:8px 0 0;color:var(--muted);font-size:.82rem;max-width:78ch}.dash__provenance{margin:0 0 14px;color:var(--muted);font-size:.78rem;font-family:var(--mono)}.dash__meters{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:20px;margin-top:14px}.dash__table{margin-top:8px;background:#fff}.dash__numeric{text-align:right;font-variant-numeric:tabular-nums}[data-testid=censoring-strip],[data-testid=role-strip]{margin-top:14px;max-width:720px}@media(max-width:780px){.dash__hero{grid-template-columns:1fr}}.kidot,.kidot__axis{display:block;overflow:visible}.kidot__grid,.kidot__rule,.kidot__tick{stroke:var(--line);stroke-width:1}.kidot__tick-label{fill:var(--muted);font-size:.68rem;font-family:var(--mono)}.kidot__mark{fill:var(--series-primary);stroke:var(--bg);stroke-width:2}@media(max-width:640px){.kidot__tick-label{font-size:.75rem}}.sdetail__heading{font-size:1.05rem;margin:0 0 8px}.sdetail__subheading{font-size:.9rem;margin:0 0 4px}.sdetail__block,.sdetail__identity{margin:0 0 30px}.sdetail__sub{color:var(--muted);font-size:.9rem;margin:0 0 12px}.sdetail__note{color:var(--muted);font-size:.85rem;margin:0 0 10px;max-width:68ch}.sdetail__absent,.sdetail__missing{color:var(--muted)}.sdetail__explain{border-left:3px solid var(--accent);background:var(--accent-soft);border-radius:0 var(--radius) var(--radius) 0;padding:12px 16px;margin:0 0 14px;max-width:78ch}.sdetail__identity-body{display:flex;flex-wrap:wrap;gap:20px 32px;align-items:flex-start}.sdetail__facts{flex:1 1 320px;margin:0;display:grid;grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:12px 24px}.sdetail__fact dt{font-size:.72rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.sdetail__fact dd{margin:2px 0 0}.sdetail__mono{font-family:var(--mono);font-size:.88rem;word-break:break-all}.sdetail__structure{margin:0;flex:0 0 auto;max-width:240px}.sdetail__structure img{width:100%;height:auto;background:#fff;border:1px solid var(--line);border-radius:var(--radius)}.sdetail__credit,.sdetail__prodrug{color:var(--muted);font-size:.78rem;margin:6px 0 0}.sdetail__prodrug{font-size:.85rem;margin-top:14px}.sdetail__sort{display:flex;flex-wrap:wrap;align-items:baseline;gap:8px 14px;margin:0 0 14px}.sdetail__sort-button{font:inherit;font-size:.82rem;color:var(--muted);background:none;border:1px solid var(--line);border-radius:999px;padding:3px 13px;cursor:pointer}.sdetail__sort-button[aria-pressed=true]{color:var(--accent);border-color:var(--accent);background:var(--accent-soft)}.sdetail__sort .sdetail__note{flex:1 1 320px;margin:0}.sdetail__group{margin:0 0 22px}.sdetail__group--bounds{border-left:3px solid var(--line);padding-left:16px}.btable__axis-label{display:block;font-size:.68rem;color:var(--muted);text-transform:none;letter-spacing:0;margin-bottom:2px}.btable__plot{width:34%;min-width:180px;vertical-align:middle;padding-top:0;padding-bottom:0}.btable td,.ptable td{vertical-align:middle}.ptable__name{display:block;font-weight:500}.ptable__path{display:block;font-family:var(--mono);font-size:.74rem;color:var(--muted)}.ptable__context{display:block;font-size:.78rem;color:var(--muted)}@media(max-width:640px){.btable__plot{width:auto;min-width:220px}.btable__axis-label{font-size:.75rem}.sdetail__facts{grid-template-columns:minmax(0,1fr)}.sdetail__sort{display:block}}.slist__controls{display:flex;flex-wrap:wrap;align-items:baseline;gap:8px 18px;margin:0 0 6px}.slist__filter{display:flex;align-items:baseline;gap:8px}.slist__filter-label{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.slist__input{font:inherit;font-size:.92rem;color:var(--ink);background:#fff;border:1px solid var(--line);border-radius:8px;padding:6px 10px;min-width:220px}.slist__input:focus-visible{outline:2px solid var(--accent);outline-offset:1px}.slist__hint,.slist__count{color:var(--muted);font-size:.85rem;margin:0;flex:1 1 320px}.slist__hint{margin:0 0 6px}.slist__count{margin:0 0 10px}.slist__empty{color:var(--muted);border:1px solid var(--line);border-radius:var(--radius);padding:18px}.slist__sort{font:inherit;font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted);background:none;border:0;padding:0;cursor:pointer;display:inline-flex;align-items:baseline;gap:5px;text-align:inherit}.slist__sort:hover{color:var(--accent)}.slist__caret{font-size:.6rem;color:var(--accent);min-width:.7em}.slist__num{text-align:right;font-variant-numeric:tabular-nums}.slist__num .slist__sort{justify-content:flex-end;width:100%}.slist__link{font-weight:500}.slist__absent{color:var(--muted);font-size:.85rem}.chip{display:inline-block;font-size:.78rem;line-height:1.5;padding:1px 9px;border-radius:999px;background:var(--accent-soft);color:var(--accent);border:1px solid var(--line);white-space:nowrap}@media(max-width:640px){.slist,.slist thead,.slist tbody,.slist tr,.slist th,.slist td{display:block}.slist thead tr{display:flex;flex-wrap:wrap;gap:6px;padding:0 0 10px;border-bottom:1px solid var(--line)}.slist thead th{padding:0;border:0}.slist tbody tr{border:1px solid var(--line);border-radius:var(--radius);padding:10px 12px;margin:0 0 10px}.slist tbody td{display:flex;align-items:baseline;justify-content:space-between;gap:12px;padding:4px 0;border:0}.slist tbody td:before{content:attr(data-label);flex:none;font-size:.78rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.slist tbody td:first-child{display:block;padding:0 0 6px}.slist tbody td:first-child:before{content:none}.slist__num{text-align:left}}@media(max-width:640px){.slist__sort{min-height:44px;padding:0 12px;border:1px solid var(--line);border-radius:999px;background:#fff;align-items:center}.slist__link{display:flex;align-items:center;min-height:44px;font-size:1.02rem}.slist__input{min-width:0;width:100%}.slist__filter{width:100%;margin:0}.slist__controls{position:sticky;top:0;z-index:2;background:var(--bg);padding:8px 0;margin:0 0 6px;border-bottom:1px solid var(--line)}}:root{--ink: #1a1626;--muted: #5c5470;--line: #e7e2f0;--bg: #fbfaff;--accent: #6b4fb0;--accent-soft: #f0ebfb;--ok: #2f855a;--warn: #b7791f;--warn-ink: #8a5a12;--mono: ui-monospace, SFMono-Regular, Menlo, Consolas, monospace;--sans: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Helvetica, Arial, sans-serif;--hero-from: #2a2140;--hero-mid: #4a3a7a;--hero-to: #6b4fb0;--series-primary: #6b4fb0;--series-secondary: #a790d6;--series-track: #f0ebfb;--series-gap: 2px;--radius: 12px;--wrap: 1080px}*{box-sizing:border-box}body{margin:0;background:var(--bg);color:var(--ink);font:16px/1.65 var(--sans);-webkit-font-smoothing:antialiased}a{color:var(--accent);text-decoration:none}a:hover{text-decoration:underline}.wrap{max-width:min(var(--wrap),100%);margin:0 auto;padding:0 24px;min-width:0}.surface__heading{font-size:1.45rem;margin:0 0 6px}.surface__sub{color:var(--muted);margin:0 0 22px}table{border-collapse:collapse;width:100%}th,td{text-align:left;padding:9px 12px;border-bottom:1px solid var(--line)}th{font-size:.76rem;text-transform:uppercase;letter-spacing:.06em;color:var(--muted)}.visually-hidden{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}@media(max-width:640px){.wrap{padding:0 16px}.shell__main{padding-top:20px}.surface__sub,.caveat__heading,.tile__label,.shell__section,.strip__caption,.istrip__caption,dt{font-size:.78rem}.caveat__heading{font-size:.8rem}.surface__sub{font-size:.95rem}.surface__heading{font-size:1.3rem}}@media(any-pointer:coarse){.shell__brand,.shell__link,.slist__input,.pmap__input,.pmap__row,.pmap__toolbar button,.pmap__filter button,.pmap__detail-clear,.agraph__input,.agraph__button,.agraph__toggle-label,.rdetail__input,.rdetail__clear,.sdetail__sort-button{min-height:44px}.shell__link,.shell__brand,.shell__skip:focus{display:flex;align-items:center}.slist__link,.rlist__link{display:flex;align-items:center;min-height:44px}.slist__sort{display:inline-flex;align-items:center;min-height:44px}.slist__num .slist__sort{justify-content:flex-end}.agraph__toggle-label input[type=checkbox]{width:22px;height:22px}.rdetail__clear{padding:0 4px}}@media(prefers-reduced-motion:reduce){*,*:before,*:after{animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important;scroll-behavior:auto!important}}